Permisol 5% Cream

Uses of Permisol 5% Cream

Scabies

How does Permisol 5% Cream work?

Permisol 5% Cream acts against scabies-causing organisms called mites. 

Side-Effects of Permisol 5% Cream

• Burning
• Tingling
• Stinging
• Itching
• Skin rashes

Quick Suggestions:

• Permisol 5% Cream is prescribed for the treatment of scabies( a condition where tiny insects infest and irritate your skin).
• It should be used as per the dose and duration suggested by your doctor.
• If the condition persists after 14 days of treatment then the doctor may suggest another treatment.
• Apply a thin layer of this medicine all over the body and leave it for 8-14 hours before taking a bath or shower.
• Avoid getting it in your eyes, nose, or mouth. If this happens, rinse with water immediately.

Pharmacology

Permethrin cream contains Permethrin, a pyrethroid, which is a topical scabicidal agent for the treatment of infestation with Sarcoptes Scabiei (scabies). It acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization & paralysis of the pests are the consequences of this disturbance.

The only approved route of administration is the topical route and there are few human data available on systemic exposure or kinetics following permethrin application to the skin. Some presystemic metabolism occurs in the skin. Less than 0.5% of applied permethrin is absorbed during the first 48 hours. Absorbed permethrin is rapidly metabolized by ester hydrolysis, most likely in the liver, and the products are excreted primarily in the urine.

Dosage of Permisol 5% Cream

Your doctor will provide instructions on how to apply Permisol 5% Cream and the appropriate amount. Be sure to follow the directions carefully. Before applying, ensure your skin is clean, dry, and cool. After application, thoroughly wash your body 8-14 hours later. Typically, a single treatment is sufficient, but if a second application is required, wait at least 7 days. Itching may persist for a few weeks after treatment, which is likely an allergic reaction to the dead mites rather than an indication that the treatment was unsuccessful.

Interaction

Since Permisol 5% Cream is to be used externally on the skin, it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions.

Contraindications

Permethrin is contraindicated in patients with known hypersensitivity to any component of pyrethroids or permethrin. Nursing staff who routinely apply permethrin may wear gloves to avoid any possible irritation to the hands.

Pregnancy & Lactation

Permisol 5% Cream is to be applied on topical surfaces and the quantities that might get absorbed from the skin are too small and there are rare chances of absorption. Still, this medicine should be used under medical supervision by a pregnant woman.

There is limited information about its effect on breast milk and breastfeeding babies. Thus, it is advised not to be applied to the breasts of breastfeeding mothers or elsewhere on large areas of skin or for a prolonged time.

Precautions & Warnings

• Please inform your doctor if you are allergic to Permisol 5% Cream, chrysanthemum, or other medicines.
• Please tell your doctor if you have any other skin diseases or chronic illnesses. Permisol 5% Cream is recommended for children below six years, elderly people, pregnant women, and breastfeeding women only if recommended by a doctor.
• Take the dose as defined by the doctor. Consult your doctor if you develop any abnormal signs or symptoms while using permethrin.

Storage:

Store in a cool and dry place away from sunlight